Brain Tumors Key Features
A variety of focal neurologic deficits result from edema, infiltration, and compression of surrounding brain tissue.
Increased ICP may also result from obstruction of the flow of CSF or displacement of the lateral ventricles by the expanding lesion.
Typically, a tumor obstructs the aqueduct of Sylvius or one of the ventricles or encroaches on the subarachnoid space.
Posterior fossa tumors may obstruct the flow of CSF from the fourth ventricle to the foramen of Luschka of Magendie.
With any brain tumor, the obstruction of normal CSF flow causes hydrocephalus and eventually leads to increased ICP.